Evaluation of acoustic radiation force impulse imaging for determination of liver stiffness using transient elastography as a reference

Table 2 Diagnostic accuracy of acoustic radiation force impulse imaging shear wave velocity and liver stiffness measured by transient elastography

	AUROC	Cut-off	PPV	NPV	Sensitivity (%)	Specificity (%)
Comparison to all patients [ARFI-SWV (n = 482)]
FS < 7.6 kPa	0.969	1.29 m/s	0.93	0.90	91.4	92.6
FS > 13.0 kPa	0.991	1.60 m/s	0.85	0.98	92.3	96.5
Comparison with liver biopsy [ARFI-SWV (n = 68) and FS-LS (n = 59)]
Non significant liver fibrosis
ARFI-SWV (n = 23)	0.929	1.32 m/s	0.83	0.91	87.0	80.0
FS-LS (n = 20)	0.920	7.6 kPa	0.85	0.95	94.9	85.0
Liver cirrhosis
ARFI-SWV (n = 28)	0.934	1.62 m/s	1.0	0.85	100	85.7
FS-LS (n = 24)	0.958	13.0 kPa	1.0	0.91	100	91.4

AUROC: Area under the receiver operating characteristic curves; CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value; ARFI-SWV: Acoustic radiation force impulse imaging shear wave velocity; FS-LS: Liver stiffness measured by transient elastography.