Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2011; 17(6): 809-816
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.809
Table 4 Correlation between K-ras mutations and clinicopathological factors in colorectal cancer n (%)
TermsAllWild typeMutation typeP value
No. of patients11877 (65.3)41 (34.7)
Gender0.037
Male7151 (71.8)20 (28.2)
Female4726 (55.3)21 (44.7)
Median age (yr)61.064.060.00.728
Males65.065.065.5
Females60.060.558.0
Colorectal segment0.559
Cecum51 (20.0)4 (80.0)
Ascending colon2317 (73.9)6 (26.1)
Transversal colon84 (50.0)4 (50.0)
Descending colon54 (80.0)1 (20.0)
Sigmoid2516 (64.0)9 (36.0)
Rectum5235 (67.3)17 (32.7)
Differentiation0.761
Poor1712 (70.6)5 (29.4)
Moderate4225 (59.5)17 (40.5)
Well5940 (67.8)19 (32.2)
UICC classification0.631
I189 (50.0)9 (50.0)
II4837 (77.1)11 (22.9)
III3723 (62.2)14 (37.8)
IV158 (53.3)7 (46.7)
Bowel wall invasion (pT)0.120
pT121 (50.0)1 (50.0)
pT22111 (52.4)10 (47.6)
pT36543 (66.2)22 (33.8)
pT43022 (73.3)8 (26.7)
Lymph node metastasis (pN)0.585
pN06947 (68.1)22 (31.9)
pN1-24931 (63.3)18 (36.7)
Distant metastasis (pM)0.301
pM010370 (68.0)33 (32.0)
pM1158 (53.3)7 (46.7)