HBV infection decreases risk of liver metastasis in patients with colorectal cancer: A cohort study

Table 1 Baseline characteristics of patients included in this study n (%)

Characteristic	Study group	Control group	P
No. of patients	332 (100)	966 (100)
Gender			NS
Male	196 (59.0)	550 (55.0)
Female	136 (41.0)	416 (45.0)
Age (yr)			NS
Median	53	60
Range	16-81	16-87
Depth of tumor invasion1	299 (100)	857 (100)	NS
T1	21 (6.3)	40 (4.1)
T2	38 (11.4)	165 (17.1)
T3	87 (26.2)	264 (27.3)
T4	153 (46.1)	388 (40.2)
Lymph-node metastasis1	295 (100)	843 (100)	NS
N0	160 (48.2)	490 (58.1)
N1	87 (26.2)	216 (25.6)
N2	48 (14.5)	137 (14.2)
Chronic liver dysfunction2	39 (11.7)	65 (6.7)	< 0.05
Albumin (g/dL)	39.4 ± 5.5	39.4 ± 11.1	NS
Total bilirubin (mg/dL)	13.0 ± 5.8	12.7 ± 6.7	NS
LDH (IU/L)	191.5 ± 141.7	197.5 ± 164.1	NS
ALP (IU/L)	71.7 ± 35.5	75.6 ± 49.7	NS
GGT (IU/L)	34.7 ± 54.9	35.4 ± 55.9	NS

¹Comparison was made only in 1156 cases after primary tumor resection, including 299 cases in tudy group and 857 cases in control group;

²Chronic hepatitis or liver cirrhosis was clinically diagnosed according to the findings in serum chemistry, ultrasonography and computed tomography. LDH: Lactate dehydrogenase; GGT: γ-glutamyl transferase; ALP: Alkaline phosphatase; NS: Not significant.