©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2011; 17(48): 5246-5259
Published online Dec 28, 2011. doi: 10.3748/wjg.v17.i48.5246
Published online Dec 28, 2011. doi: 10.3748/wjg.v17.i48.5246
Table 2 Predicted future developments in the genetics of Crohn’s disease
| What lies ahead in the genetics of crohn’s disease |
| Gene-to-gene crosstalk and epistasis |
| Genome-wide association studies |
| Microarrays |
| Fine single nucleotide polymorphism analysis |
| Genetic consortium studies and genome-wide scans |
| Genome-wide association studies |
| Genetic consortium studies |
| Future perspectives |
| Functional studies to understand the mechanisms |
| Combining genetic data with functional data |
| Combination of a panel of clinical, biochemical, serological and genetic factors |
| Functional consequences of polymorphisms |
| Molecular and cellular mechanisms leading to Crohn’s disease |
| Predict disease outcomes |
| Redesigning the methods of treatment |
- Citation: Tsianos EV, Katsanos KH, Tsianos VE. Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol 2011; 17(48): 5246-5259
- URL: https://www.wjgnet.com/1007-9327/full/v17/i48/5246.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i48.5246