Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation

doi:10.3748/wjg.v17.i45.5007

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Dec 7, 2011 (publication date) through Sep 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2011; 17(45): 5007-5013
Published online Dec 7, 2011. doi: 10.3748/wjg.v17.i45.5007

Table 6 Multivariate analysis of the association between rate of liver fibrosis (slow fibrosers vs fast fibrosers) predicted by prothrombin 20210 mutation and various known parameters

Parameter	OR (95% CI)	P-wald¹
Age	0.91 (0.86-0.96)	< 0.001
PT20210	4.76 (1.13-19.99)	0.033
Inflammation grade²	7.42 (3.07-17.95)	< 0.001

Variables removed from the model: gender, BMI and alcohol consumption.

¹The Wald test was used to assess the significance of each logit;

²Inflammation was categorized: grades 0 and 1 compared with grades 2 and 3. PT20210: Prothrombin 20210; OR: Odds ratio; CI: Confidence interval.

Citation: Maharshak N, Halfon P, Deutsch V, Peretz H, Berliner S, Fishman S, Zelber-Sagi S, Rozovski U, Leshno M, Oren R. Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation. World J Gastroenterol 2011; 17(45): 5007-5013
URL: https://www.wjgnet.com/1007-9327/full/v17/i45/5007.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i45.5007