Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation

Table 3 Percentage of hypercoagulation gene mutation carriage by rate of fibrosis (by Poynard)

Gene	Mutation carriage	Percent of slow fibrosers	Percent of fast fibrosers	P value
PT20210	Wild type	94.5	86.9	0.181
	Heterozygote	5.5	10.9
	Homozygote	0	2.2
Factor V Leiden	Wild type	95.5	98	0.67
	Heterozygote	4.5	2
	Homozygote	0	0
MTHFR	Wild type	35.6	36	0.80
	Heterozygote	52	48
	Homozygote	12.4	16

¹Heterozygote and homozygote categories were unified for Fisher's exact test. PT20210: Prothrombin 20210; MTHFR: Methylene tetrahydrofolate reductase.