Plasma DNA methylation of Wnt antagonists predicts recurrence of esophageal squamous cell carcinoma

Figure 1 Receiver operating characteristic curve analysis to assess the sensitivity and specificity of the status of methylated genes in combination with the stage for predicting esophageal squamous cell carcinoma recurrence using the “pROC” package in R. Combination of 2-3 genes, area under curve (AUC) = 77.1, sensitivity = 66.67, specificity = 83.3, stage, AUC = 75.24, sensitivity = 71.43, specificity = 78.3, combination of 2-3 genes + stage, AUC = 83.69, sensitivity = 76.19, specificity = 83.3.