Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer

Table 6 Multivariate analysis of 37 patients with advanced colorectal cancer treated by cetuximab-containing chemotherapy

	B	SE	Wald	P value	OR	95.0% CI for OR
						Lower	Upper
Primary clinical stage	1.52	0.43	12.63	0.00	4.55	1.97	10.51
Histological grade	-0.06	0.54	0.01	0.92	0.95	0.33	2.72
Beclin-1 expression	-0.09	0.08	1.14	0.29	0.92	0.78	1.08
LC3 expression	0.01	0.10	0.01	0.92	1.01	0.83	1.22
KRAS status	0.52	0.46	1.27	0.26	1.68	0.68	4.15

Thirty-seven of 45 cases were included in COX regression model because the KRAS status of 8 patients was not available. B: Regression coefficient; SE: Standard Error; OR: Odds ratio; CI: Confidence Interval.