Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption

Table 5 Performance of tests for Helicobacter pylori infection

	Sensitivity% (95% CI)	Specificity% (95% CI)	PPV% (95% CI)	NPV% (95% CI)	Accuracy(%)	False positive(%)	False negative(%)
Culture of biopsy specimens	38/44	36/36	38/38	36/42	74/80	0/36	6/44
	86.4 (72.7-94.8)	100 (90.3-100)	100 (90.8-100)	85.7 (71.5-94.6)	-92.5	0	-13.6
Helicobacter pylori on tissue sections	29/44	28/36	29/37	28/43	57/80	8/36	15/44
	65.9 (50.1-79.5)	77.8 (60.9-89.9)	78.4 (61.8-90.2)	65.1 (49.1-79.0)	-71.3	-22.2	-34.1
Rapid urease test	30/44	27/36	30/39	27/41	57/80	9/36	14/44
	68.2 (52.4-81.4)	75.0 (57.8-87.9)	76.9 (60.7-88.9)	65.9 (49.4-79.9)	-71.3	-25	-31.8
Helicobacter pylori on tissue sections and rapid urease test	25/44	36/36	25/25	36/55	61/80	0/36	19/44
	56.8 (41.0-71.7)	100 (90.3-100)	100 (86.3-100)	65.5 (51.4-77.8)	-76.3	0	-43.2
Anti-CagA	26/44	26/36	26/36	26/44	52/80	10/26	18/44
	59.1 (43.3-73.7)	72.2 (54.8-85.8)	72.2 (54.8-85.8)	59.1 (43.3-73.7)	-65	-38.5	-40.9

CI: Confidence interval; NPV: Negative predictive value; PPV: Positive predictive value.