Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis

Figure 1 Time-sequence of the healing of trinitrobenzenesulfonic acid-induced colonic lesions, and accompanying changes in the colonic blood flow following day 1, 3, 10 and 14 upon induction of colitis. The area of trinitrobenzenesulfonic acid-induced lesions was maximal on day 1 and then it significantly declined on day 10 and day 14, respectively. Mean ± SE of 6-8 rats. ^aP < 0.05 vs values obtained on day 3; ^cP < 0.05 vs values on day 3 and day 10. TNBS: Trinitrobenzenesulfonic acid; CBF: Colonic blood flow.