Prediction of nephrotoxicity induced by cisplatin combination chemotherapy in gastric cancer patients

Table 4 Comparison between the cycle during which nephrotoxicity occurred and the amount of accumulated cisplatin according to renal status post-acute renal failure (ARF)

	Renal status post-ARF		P value3
	Recovered1 (n = 33)	Unrecovered2 (n = 8)
The cycle nephrotoxicity occurred	4.24 ± 2.09	6.63 ± 2.62	0.009
The cumulative dose of cisplatin/BSA, mg	302.85 ± 152.73	497.75 ± 222.61	0.005

¹Recovered were patients whose serum creatinine (SCR)s had decreased below 1.5 mg/dL after acute renal failure.

²Unrecovered were patients whose SCRs remained greater than 1.5 mg/dL.

³Unpaired Student’s t–test. ARF: Acute renal failure; BSA: Body surface area.