Liver function alterations after laparoscopy-assisted gastrectomy for gastric cancer and its clinical significance

Table 1 Patient characteristics n (%)

Variables	Stomach cancer (n = 215)			Colon cancer (n = 121)
	LAG (n = 91)	OG (n = 124)	P	LAC (n = 43)	OC (n = 78)	P
Gender (M:F)	70:21	94:30	NS	22:21	43:35	NS
Age (yr, mean ± SD)	57.1 ± 13.2	59.7 ± 11.9	NS	58.9 ± 10.3	62.0 ± 13.5	NS
BMI (kg/m2, mean ± SD)	23.8 ± 3.2	23.5 ± 3.4	NS	24.2 ± 3.6	24.7 ± 2.9	NS
Underlying liver disease			NS			NS
No	81 (89.0)	103 (83.1)		30 (69.8)	66 (84.6)
Yes	10 (11.0)	21 (16.9)		13 (30.2)	12 (15.4)
Fatty liver	6	9		11	8
Hepatitis	4	12		2	4
TNM stage			< 0.001			0.004
I	84 (92.3)	53 (42.7)		18 (41.9)	15 (19.2)
II	4 (4.4)	22 (17.7)		8 (18.6)	35 (44.9)
III	3 (3.3)	30 (24.3)		17 (39.5)	28 (35.9)
IV	0	19 (15.3)		0	0
Operation time (min, mean ± SD)	230.1 ± 77.6	165.2 ± 52.1	< 0.001	252.5 ± 77.2	184.1 ± 62.4	< 0.001
Combined operation			0.004			NS
No	80 (87.9)	89 (71.8)		42 (97.7)	74 (94.9)
Yes	11 (12.1)	35 (28.2)		1 (2.3)	4 (5.1)
Anesthetic agent			NS			NS
Sevoflurane	21 (23.1)	45 (36.3)		15 (34.9)	18 (23.1)
Desflurane	70 (76.9)	79 (63.7)		28 (65.1)	60 (76.9)
Postoperative morbidity	8 (8.8)	16 (12.9)	NS	1 (2.3)	5 (6.4)	NS
Postoperative mortality	1	1		1	0
Hospital stay (d, mean ± SD)	10.7 ± 16.0	14.9 ± 12.6	NS	12.7 ± 3.8	17.9 ± 12.3	0.007

LAG: Laparoscopy-assisted gastrectomy; OG: Open gastrectomy; LAC: Laparoscopy-assisted colectomy; OC: Open colectomy; BMI: Body mass index; NS: Not significant.