Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients

Table 3 Characteristics of the patients with flare-ups of hepatitis

Patient	Age (yr)	Sex	Cirrhosis	HBeAg	Change of HBV DNA level after treatment (log copies/mL)			Mutant type
					Pre-treatment	Nadir	Virological breakthrough with hepatitis flare-ups
1	54	F	+	+	8.7	4.7	7.6	YIDD/YVDD
2	56	M	+	+	8.1	4.1	7.9	Mixed
3	59	M	+	-	6.6	< 2.6	6.8	YIDD
4	60	M	+	+	7.9	< 2.6	8	Mixed
5	65	M	+	+	6.5	< 2.6	6.7	Mixed
6	49	M	+	+	7.9	3.9	7	YIDD
7	58	M	-	+	8.7	3.9	7.2	YVDD
8	51	M	-	+	7.8	3.8	7.6	YIDD/YVDD
9	58	M	-	+	8.7	4.3	7.9	Mixed
10	61	M	+	-	6	< 2.6	6.6	Mixed
11	51	F	-	+	7.2	< 2.6	5.9	YIDD
12	62	F	-	+	7.7	< 2.6	6.6	Mixed
13	44	M	+	+	6.7	< 2.6	5.9	YVDD
14	56	M	-	+	8.7	5	7	YVDD
15	50	F	-	+	7.6	5.6	6.2	YIDD
16	47	M	+	+	7.9	3.9	6.4	YIDD
17	59	F	+	-	6.9	< 2.6	6.1	YVDD
18	45	M	-	-	6.9	< 2.6	6.1	Mixed
19	61	M	-	-	6.7	< 2.6	5.9	Mixed
20	56	M	+	-	6.6	< 2.6	5.7	YVDD

HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen.