Log-normal censored regression model detecting prognostic factors in gastric cancer: A study of 3018 cases

Table 2 Univariate model of Cox and log normal regression with prognostic factors

	HR (95% CI)
	Cox	Log normal
Sex
Male	0.953 (0.843-1.078)	0.925 (0.818-1.046)
Female	1.00	1.00
Age at diagnosis	1.0151 (1.009-1.020)	1.0161 (1.011-1.021)
Past history
Without	1.00	1.00
With	0.7151 (0.631-0.831)	0.6941 (0.612-0.787)
Family history
Without	1.00	1.00
With	0.871 (0.752-1.009)	0.875 (0.754-1.014)
Cancer number
Single	1.00	1.00
Multiple	0.870 (0.622-1.218)	0.924 (0.661-1.294)
Cancer location
Lower third	1.00	1.00
Middle third	1.1811 (1.017-1.373)	1.3021 (1.233-1.374)
Upper third	1.4361 (1.212-1.701)	1.6951 (1.429-1.897)
Total stomach	2.4641 (2.062-2.944)	2.2071 (2.011-2.677)
Distant metastasis
Absent	1.00	1.00
Present	2.5541 (2.194-2.973)	2.5961 (2.227-3.027)
Surgical curative degree
Absolutely radical	1.00	1.00
Relatively radical	1.8351 (1.593-2.114)	2.1591 (2.020-2.308)
Palliative	4.2361 (3.714-4.832)	4.6611 (4.214-4.759)
Lymph node dissection
> D2	1.00	1.00
D2	0.989 (0.859-1.138)	1.5361 (1.458-1.619)
D1	1.056 (0.853-1.307)	2.3591 (2.121-2.574)
< D1	3.3101 (2.854-3.839)	3.6241 (3.231-3.862)
Combined other organ resection
Without	1.00	1.00
With	1.9811 (1.749-2.245)	2.0701 (1.825-2.348)
Histologic types
Well differentiated	1.00	1.00
Middle differentiated	0.7061 (0.592-0.843)	0.976 (0.918-1.039)
Poor differentiated	0.918 (0.814-1.036)	0.952 (0.897-1.011)
Borrmann classification (n (%))
I	1.00	1.00
II	1.005 (0.892-1.340)	0.981 (0.894-1.019)
III	1.2471 (1.173-1.638)	1.1761 (1.074-1.293)
IV	2.5121 (1.842-3.075)	2.6101 (2.416-3.153)
Lauren classification (n (%))
Intestinal type	1.00	1.00
Diffuse type	1.2451 (1.082-1.184)	1.1711 (1.015-1.384)
pT stage
pT1	1.00	1.00
pT2	2.9361 (2.299-3.751)	1.7871 (1.666-1.916)
pT3	4.3051 (3.357-5.522)	3.1931 (3.066-3.321)
pT4	7.6971 (5.759-10.287)	5.7071 (5.579-5.833)
Total dissected nodes	0.9931 (0.988-0.998)	0.9941 (0.988-0.998)
pN stage
pN0	1.00	1.00
pN1	1.5551 (1.372-1.764)	1.6331 (1.533-1.740)
pN2	2.5101 (2.133-2.953)	2.6671 (2.561-2.772)
pN3	3.6691 (2.901-4.640)	4.3551 (4.249-4.460)

¹Statistically significant (P < 0.05). HR: Hazard radio; CI: Confidence interval.