microRNAs: Fad or future of liver disease

Table 1 Differentially expressed microRNAs in liver development and disease

Liver status	Upregulated miRs	Downregulated miRs	Ref.
Development	122, 92a, 483, 486-5p, 30 family	22, let 7 family, 199a, 21	[6,21]
NASH/NAFLD	34a, 146b, 200a, 224, 222, 10b, 22, 33, 31, 29c	122, 181d, 132, 150, 28-3p, 511, 517a, 671-3p, 99b, 433	[14-16]
HCV	122, let 7f, 155, 146, 296, 351, 128, 296, 141	196, 15a, 15b, 17, 106a, 106b, 181a, 29a, 29b, 93, 310, 30a, 30c, 24, 221, 222	[24,26,27]
ALD	705, 1224, 212	182, 183, 199a-3p, 199, NSC/NPC: 9, 21, 153, 335	[18,34]
Fibrosis	125-5p, 199b, 221, 302c, 223, 34c, 24	29a, 29b, 29c, 30b, 30c, 183, 96, 877, 341, 193, 132	[40,42]
Regeneration	21, 130a, 181b, 20a, 20b	378, 689, 7	[48,49]

NSC: Neural stem cell; NPC: Neural progenitor cell; miRs: microRNAs; HCV: Hepatitis C virus; ALD: Alcoholic liver disease; NAFLD: Nonalcoholic fatty liver disease; NASH: Nonalcoholic steatohepatitis.