Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2011; 17(2): 219-225
Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.219

Table 1 Patient and tumor characteristics n (%)

Patients (n = 41)
Age (yr)
mean ± SD	47 ± 14
Range	20-77
Sex
Male	17 (41.5)
Female	24 (58.5)
Tumor type
Carcinoid	12 (29.3)
Functional PNET	19 (46.3)
Non-functional PNET	10 (24.4)
Tumor grade
Well-differentiated NET	13 (31.7)
Well-differentiated NEC	26 (63.4)
Poorly differentiated NEC	1 (2.4)
Unknown	1 (2.4)
Metastases
Present	26 (63.4)
Lymph node only	9 (34.6)
Liver only	7 (26.9)
Both	10 (38.5)
Absent	15 (36.6)
Tumors (n = 60)
Primary or metastatic tissues
Primary	45 (75.0)
Metastasis	15 (25.0)
Angio-invasion
Present	11 (18.3)
Absent	49 (81.7)
Tumor size (mean ± SD, cm)
Carcinoids	3.4 ± 2.7
Functional PNETs	1.9 ± 1.7
Non-functional PNETs	3.6 ± 2.4

PNETs: Pancreatic neuroendocrine tumors; NET: Neuroendocrine tumor; NEC: Neuroendocrine carcinoma.

Citation: Kuiper P, Hawinkels LJ, Jonge-Muller ES, Biemond I, Lamers CB, Verspaget HW. Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors. World J Gastroenterol 2011; 17(2): 219-225
URL: https://www.wjgnet.com/1007-9327/full/v17/i2/219.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i2.219

Kuiper P, Hawinkels LJ, Jonge-Muller ES, Biemond I, Lamers CB, Verspaget HW. Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors. World J Gastroenterol 2011; 17(2): 219-225 [PMID: 21245995 DOI: 10.3748/wjg.v17.i2.219]

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