Inhibitory effect of schisandrin B on free fatty acid-induced steatosis in L-02 cells

Figure 5 Effect of schisandrin B on mRNA and protein expression levels of several lipid metabolism-related molecules in free fatty acid-treated L-02 cells. A, B: Semi-quantitative polymerase chain reaction (PCR) and real-time quantitative PCR showing mRNA levels of adipose differentiation related protein (ADRP), sterol regulatory element binding protein 1 (SREBP-1), peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ. Results shown are the representative of three independent experiments. ^aP < 0.05, ^bP < 0.01 vs control group; ^cP < 0.05 vs free fatty acid-treated groups; C: Immunoblotting showing expression levels of ADRP and SREBP-1 proteins. The representative blots out of three experiments are shown. FFA: Circulating free fatty acid; Sch B: Schisandrin B.