CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma

Table 4 Relationship between CXC chemokine receptor-4 expression and clinicopathological features in gastric cancer

Clinicopathologic parameters	No.	CXC chemokine receptor-4
		Positive	Negative	χ2	P value
Sex
Male	31	18	13	0.006	0.9382
Female	9	6	3
Age (yr)
> 56	19	12	7	0.007	0.9351
≤ 56	21	13	8
Tumor size (cm)
≥ 5	25	16	9	0.064	0.8001
< 5	15	9	6
Tumor location
Cardia of stomach	2	2	0	-	0.8113
Fundus of stomach	1	1	0
Body of stomach	6	4	2
Antrum of stomach	31	18	13
Differentiation
Moderate/well	6	1	5	-	0.0213
Poor	34	24	10
Lymph node metastasis
Present	32	26	6	4.146	0.0422
Absent	8	3	5
Stage
II and IIIa	23	8	15	5.013	0.0251
IIIb and IV	17	12	5

¹χ² test;

²Modified χ² test;

³Fisher exact test.