LBP and CD14 polymorphisms correlate with increased colorectal carcinoma risk in Han Chinese

Table 2 Genes, polymorphism and frequencies in colorectal carcinoma cases and controls

SNP	Genotype	Cases (n = 479)	Controls (n = 486)	Odds ratio (95% CI)	1P value
LBP
rs1739654	GG	377 (78.7%)	360 (74.1%)
	GA	93 (19.4%)	118 (24.3%)	0.75 (0.55-1.02)	0.07
	AA	9 (1.9%)	8 (1.6%)	1.07 (0.41-2.82)	0.88
	GA+AA	102 (21.3%)	126 (25.9%)	0.77 (0.57-1.04)	0.09
rs2232596	AA	289 (60.3%)	343 (70.6%)
	GA	169 (35.3%)	133 (27.4%)	1.51 (1.15-1.99)	0.003
	GG	21 (4.4%)	10 (2%)	2.49 (1.16-5.38)	0.016
	GA+GG	190 (39.7%)	143 (29.4%)	1.58 (1.21-2.06)	0.001
rs2232618	TT	385 (80.4%)	396 (81.5%)
	CT	93 (19.4%)	88 (18.1%)	1.09 (0.79-1.50)	0.613
	CC	1 (0.2%)	2 (0.4%)	0.51 (0.05-5.70)	0.581
	CT+CC	94 (19.6%)	90 (18.5%)	1.07 (0.78-1.48)	0.662
CD14
rs77083413	GG	403 (84.1%)	400 (82.3%)
	GC	70 (14.6%)	81 (16.7%)	0.858 (0.605-1.215)	0.388
	CC	6 (1.3%)	5 (1%)	1.19 (0.36-3.93)	0.774
	GC+CC	76 (15.9%)	86 (17.7%)	0.88 (0.63-1.23)	0.447
rs4914	CC	369 (77%)	415 (85.4%)
	CG	102 (21.3%)	68 (14%)	1.69 (1.20-2.36)	0.002
	GG	8 (1.7%)	3 (0.6%)	3.00 (0.79-11.39)	0.091
	CG+GG	110 (23%)	71 (14.6%)	1.74 (1.25-2.42)	0.001
IL-6
rs13306435	TT	415 (86.6%)	420 (86.4%)
	AT	60 (12.5%)	65 (13.4%)	0.93 (0.64-1.36)	0.723
	AA	4 (0.9%)	1 (0.2%)	4.05 (0.45-36.37)	0.177
	AT+AA	64 (13.4%)	66 (13.6%)	0.98 (0.68-1.42)	0.921

¹Adjusted for age, sex, smoking and drinking status.