Soluble ST2: A new and promising activity marker in ulcerative colitis

Table 3 Correlation data of endoscopic and histopathological scores with serum sST2, interleukin-33, interleukin-6, tumor necrosis factor-α levels and total intestinal ST2

Disease activity index	Endoscopic score	Histopathological score
sST2 (pg/mL)
r	0.7624	0.6762
P-value	< 0.0001	< 0.0001
IL-33 (pg/mL)
r	0.2869	0.1687
P-value	0.0146	0.1657
IL-6 (pg/mL)
r	0.2315	0.0888
P-value	0.0676	0.2855
TNF-α (pg/mL)
r	0.6961	0.6112
P-value	< 0.0001	< 0.0001
Intestinal ST2 (pg/mL per mg protein)
r	0.6267	0.6034
P-value	< 0.0001	< 0.0001

IL: Interleukin; TNF: Tumor necrosis factor; r: Spearman’s rank correlation coefficient.