Trefoil factors: Tumor progression markers and mitogens via EGFR/MAPK activation in cholangiocarcinoma

Table 4 Relative copy number of trefoil factor genes in cholangiocarcinoma

No.	TFF1	TFF2	TFF3
1	2.031	1.691	2.311
2	1.431	1.371	1.721
3	1.551	1.371	2.341
4	2.001	2.191	2.911
5	1.461	1.731	1.841
6	1.791	1.781	3.211
7	1.821	2.741	3.671
8	1.441	0.96	1.381
9	1.551	0.98	1.781
10	1.551	0.99	1.561
11	1.681	1.30	2.361
12	1.681	1.10	1.401
13	1.971	0.85	2.171
14	1.611	1.33	2.321
15	1.581	1.00	1.581
16	1.621	1.22	2.891
17	1.491	1.17	1.351
18	1.521	0.97	2.251
19	1.621	1.21	1.851
20	1.14	1.10	1.551
21	1.17	0.98	1.661
22	0.83	0.92	1.571
23	1.14	1.03	1.481
24	0.98	1.14	1.411
25	1.06	1.15	1.651
26	1.06	1.33	2.131
27	1.32	0.91	1.421
28	1.20	1.01	1.571
29	1.27	1.631	1.851
30	1.32	1.891	1.581
31	1.29	2.681	2.161
32	1.28	1.381	1.871
33	0.88	1.481	1.631
34	1.491	1.421	1.24
35	1.381	0.71	0.99
36	1.771	1.03	1.12
37	1.381	0.92	1.29
38	1.511	1.17	0.94
39	1.521	1.02	1.23
40	1.461	1.12	1.34
41	1.421	0.97	1.34
42	1.371	0.73	0.79
43	0.84	0.472	0.58
44	0.63	0.372	0.88
45	0.68	0.532	0.86
46	0.63	0.512	0.83
47	0.86	0.382	0.55
48	0.76	0.422	0.462
49	0.92	0.68	0.452
50	0.82	0.85	0.512
51	1.07	0.79	0.97
52	1.15	0.59	1.11
53	0.95	0.84	1.02
54	0.84	0.79	0.68
55	0.74	0.77	1.26
56	0.77	1.03	0.83
57	1.13	1.31	1.26
58	1.13	1.03	1.20
59	1.00	0.88	0.89
60	1.17	0.70	1.15
61	0.94	0.91	1.19
62	0.76	0.72	0.63
63	1.15	1.04	1.15
64	1.25	0.95	0.87
65	1.01	0.77	0.90
66	1.11	1.27	1.03
67	0.85	0.62	0.54
68	1.10	0.96	1.23
69	1.06	0.92	0.84
70	1.05	0.88	0.80
71	1.12	1.09	1.10
72	1.33	0.87	1.22
73	0.87	1.01	0.71
74	0.75	0.88	0.76
75	1.04	0.74	1.14
76	1.10	0.67	0.93
77	1.06	0.98	1.14
78	1.10	0.97	1.30
79	1.22	0.87	1.21
80	1.16	0.95	1.32
81	1.13	1.07	1.32
82	1.10	0.88	1.24
83	0.92	1.05	1.31
84	1.14	0.97	1.09
85	1.01	0.98	1.14
86	1.13	1.07	1.26
87	0.91	0.59	1.23
88	0.97	0.69	1.16
89	0.91	0.78	0.91
90	1.06	0.71	1.06
91	1.15	0.69	0.88
92	0.96	0.58	0.57
93	1.03	1.00	1.30
94	1.20	0.93	1.06
95	1.25	0.76	0.77
96	1.28	1.21	1.24
97	1.28	1.15	0.94
98	1.10	0.82	0.99
99	1.28	0.73	0.71
100	0.87	0.59	0.91
101	1.05	0.78	1.28
102	1.00	0.70	0.99
103	0.66	0.61	0.61
104	0.89	0.74	0.80
105	0.88	0.57	0.60
106	0.82	0.56	0.58
107	1.04	1.05	1.04
108	0.90	0.98	0.88
109	0.65	0.65	0.64
110	1.18	1.21	1.20

Figures indicate relative copy number of trefoil factor (TFF) genes (TFF1, TFF2, TFF3) compared to the reference gene, β-actin.

¹Amplification;

²Deletion. Other figures are normal.