Optical molecular imaging for detection of Barrett’s-associated neoplasia

Table 2 Summary of performance of emerging optical technologies

Type of detection	Study size	Sensitivity, specificity
AFI	60 patients, 116 images	91%, 43%[36]
NBI	63 patients, 175 images	94%, 76%[33]
	51 patients, 204 images	100%, 98%[34]
	21 patients, 75 images	89%, 95%[38]
High-resolution imaging (1-15 μm resolution)
OCT	33 patients, 314 images	68%, 82%[43]
	55 patients, 177 images	83%, 75%[58]
Endocytoscopy	16 patients, 166 images	56%, 68% (425 ×)
		42%, 83% (1125 ×)[47]
Confocal imaging	63 patients, 433 images	93%, 98%[48]
	38 patients, 296 images	75%, 90%[50]

AFI: Autofluorescence imaging; OCT: Optical coherence tomography; NBI: Narrow-band imaging.