Oxidative stress and antioxidants in hepatic pathogenesis

Figure 1 Increased reactive oxygen species in hepatitis B virus X protein transfected HepG2 stable cell line and hepatitis B virus X protein transgenic mouse hepatocytes. Reactive oxygen species (ROS) was detected by FACS caliber using dichlorofluorescein diacetate (DCFA-DA). A: HepG2 cell line stably transfected with hepatitis B virus X protein (HBx) showed a higher level of ROS compared to control cells; B: ROS production was checked after 4 wk of male HBx and control mouse hepatocyte growth. HBx mice hepatocytes generate more ROS than control mice.