Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 14 Energy metabolism in stomach tissue (mean ± SE)

Group	ATP (μmol/mg protein)	ATP loss (%)	ADP/ATP ratio
Stress (-)
Veh	13.4 ± 0.9	0.0 ± 6.7	0.16 ± 0.02
Cer	12.9 ± 0.7	3.7 ± 5.2	0.18 ± 0.03
Anti-TNF-α + Cer	13.0 ± 0.8	3.0 ± 6.0	0.17 ± 0.02
Stress (+)
Veh	5.5 ± 0.4a	58.9 ± 3.0a	0.67 ± 0.07a
Cer	2.3 ± 0.4a	82.8 ± 3.0a	1.14 ± 0.16a
Anti-TNF-α + Cer	6.2 ± 0.6c	53.7 ± 4.5c	0.58 ± 0.06c

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α.