Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 13 Stomach caspases (mean ± SE)

Group	CASP-2	CASP-3	CASP-8	CASP-9
Stress (-)
Veh	37 ± 4	32 ± 3	48 ± 5	39 ± 5
Cer	40 ± 5	32 ± 5	51 ± 4	40 ± 3
Anti-TNF-α + Cer	33 ± 4	30 ± 3	47 ± 4	39 ± 4
Stress (+)
Veh	1358 ± 132a	1515 ± 154a	1479 ± 136a	1425 ± 126a
Cer	798 ± 87a	824 ± 95a	868 ± 70a	832 ± 87a
Anti-TNF-α + Cer	1089 ± 98c	1203 ± 107c	1108 ± 89c	1144 ± 102c

Stomach caspases are expressed as pmol/min per milligram protein.

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α; CASP: Caspase.