Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 10 Lung caspases (mean ± SE)

Group	CASP-2	CASP-3	CASP-8	CASP-9
Stress (-)
Veh	18 ± 3	20 ± 2	21 ± 5	22 ± 4
Cer	27 ± 3	29 ± 4	32 ± 5	29 ± 3
Anti-TNF-α + Cer	26 ± 2	24 ± 3	24 ± 4	22 ± 3
Stress (+)
Veh	97 ± 11	103 ± 9	99 ± 8	104 ± 12
Cer	853 ± 81a	912 ± 101a	824 ± 77a	917 ± 85a
Anti-TNF-α + Cer	597 ± 48c	592 ± 55c	560 ± 45c	568 ± 47c

Lung caspases are expressed as pmol/min per milligram protein.

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α; CASP: Caspase.