Transient elastography in chronic hepatitis B: An Asian perspective

doi:10.3748/wjg.v16.i41.5173

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2010; 16(41): 5173-5180
Published online Nov 7, 2010. doi: 10.3748/wjg.v16.i41.5173

Table 4 Histologic distribution and the performance of transient elastography for the diagnosis of liver fibrosis in patients with chronic hepatitis B

	n (%)					METAVIR and other scoring system (≥ F2/F4)
	F0	F1	F2	F3	F4	AUROC	Cutoff (kPa)	Se (%)	Sp (%)	PPV (%)	NPV (%)	LR (+)	LR (-)
Kim et al[4]	0	9 (9.9)	33 (36.3)	10 (11.0)	39 (42.9)	-/0.803	-/9.7	-/82	-/62	-/63	-/76	-/4.97	-/0.13
Chan et al[11]	10 (6.2)	27 (16.8)	47 (29.2)	37 (23.0)	40 (24.8)	-/0.93	-/9	-/98	-/75	-/57	-/98	-/1	-/0.01
Kim et al[36]	0	10 (7.7)	37 (28.5)	16 (12.3)	67 (51.5)	-/0.84	-/10.1	-/76	-/81	-/76.1	-/80.9	-/-	-/-
Marcellin et al[10]	16 (9.2)	70 (40.5)	44 (25.4)	29 (16.8)	14 (8.1)	0.81/0.93	7.2/11	70/98	83/75	80/57	73/98	4/1	-/0.01
Chang et al[40]	7 (20.0)	16 (45.7)	F2-3 (5, 14.3)		7 (20.0)	-/-	11.8/-	90/-	78/-	-/-	-/-	-/-	-/-
Tanwandee et al[41]	-	-	-	-	-	0.757/-	6.9/7.3	70/93	79/61	82/31	66/98	-/-	-/-
Choi et al[42]	-	-	-	-	-	0.88/0.86	7.7/10.4	88/79	88/83	-/-	-/-	-/-	-/-
Chang et al[43]	-14.8	-30.7	-14.8	-21.6	-17.1	0.801/-	8.8/-	-/-	-/-	-/-	-/-	-/-	-/-

AUROC: Area under the receive operating characteristic curve; Se: Sensitivity, Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; LR: Likelihood ratio.

Citation: Kim SU, Han KH, Ahn SH. Transient elastography in chronic hepatitis B: An Asian perspective. World J Gastroenterol 2010; 16(41): 5173-5180
URL: https://www.wjgnet.com/1007-9327/full/v16/i41/5173.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i41.5173