Terlipressin and hepatorenal syndrome: What is important for nephrologists and hepatologists

Table 1 Summary of effect of terlipressin associated with albumin on hepatorenal syndrome

Study	Main outcome
Sanyal et al[72], 2008	Terlipressin administration with albumin shown to be associated with improvement in renal function and appeared superior to placebo in reversing type 1 HRS
Martín-Llahí et al[73], 2008	Terlipressin administration with albumin shown to be associated with improvement in renal function in patient with liver cirrhosis and type 1 HRS, without significant impact on 3-mo survival
Neri et al[74], 2008	Terlipressin administration with albumin shown to be associated with improvement in renal function in patients with type 1 HRS and also a high probability of survival
Uriz et al[17], 2000	Terlipressin associated with albumin appeared to be a safe and effective treatment of HRS and decreased the frequent ischemic complications associated with terlipressin treatment alone. Terlipressin associated with albumin therapy was associated with marked improvement in renal function, reversal of HRS and improvement in circulatory function with an increase in mean arterial blood pressure

HRS: Hepatorenal syndrome.