Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis

Figure 1 Effect of Mangifera indica L. on weight gain in dextran sulfate sodium-treated rat ulcerative colitis. Experimental colitis was induced by 4% dextran sulfate sodium (DSS) dissolved in drinking water for 7 d. Control group received common water; Group A was exposed to 4% DSS and vehicle; Group B was co-treated with rectal Mangifera indica L. (MIE) for 7 d, at the same time as DSS administration; Group C was treated with MIE (150 mg/kg) orally during 14 d prior to DSS administration, and co-administered rectally during DSS exposure. Each bar represents the difference between the weight at the beginning and ending of the experiment, and it was expressed as the mean ± SE of each group. ^aSignificant differences vs control group; ^cSignificant differences vs group A; P < 0.05.