Etiology and long-term outcome of extrahepatic portal vein obstruction in children

Table 1 Demographic data, clinical presentation and risk factors for extrahepatic portal vein obstruction in the study group

	n (%)
Gender
Male	13 (43.3)
Female	17 (56.7)
Ethnicity
Jewish	15 (50)
Arab	14 (46.6)
Russian	1 (3.3)
Referral
Israeli	19 (63.3)
Palestinian	11 (36.7)
Gestational age
Term	23 (76.7)
Preterm	7 (23.3)
Clinical presentation
Splenomegaly	13 (43.3)
UGI bleeding	12 (40.0)
Cytopenia	5 (16.6)
Elevated liver enzymes	2 (6.6)
Risk factor for EHPVO
Perinatal events
Umbilical catheterization	6 (20)
Omphalitis	2 (6.6)
Sepsis, NEC	1 (3.3)
Hypercoagulable state
APLA syndrome	2 (6.6)
Protein S and C deficiency	1 (3.3)
MTHFR mutation homozygosity	1 (3.3)
Unknown	17 (56.6)

EHPVO: Extrahepatic portal vein obstruction; UGI: Upper gastrointestinal; MTHFR: Methyltetrahydrofolate reductase; APLA: Anti phospholipid antibodies.