Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients

Table 1 Comparison of clinical parameters between anti-nuclear envelope antibody positive and anti-nuclear envelope antibody negative patients (mean ± SD) n (%)

	ANEA		P value
	Positive	Negative
Patients	69 (46.9)	78 (53.1)
Age (yr)	59.3 ± 11.8	59.1 ± 10.1	0.330
AMA titer ≤ 1:160/> 1:1601	35 (50.7)/34 (49.3)	56 (71.8)/22 (28.2)	0.001
Stage I-II/stage III-IV	39 (56.5)/30 (43.5)	58 (74.4)/20 (25.6)	0.005
Alive/dead	51 (77.3)/15 (22.7)	66 (86.8)/10 (13.2)	0.162
Survival	91.7 ± 50.7	101.8 ± 55	0.043
Mayo risk score	5.19 ± 1.8	5.04 ± 1.3	0.239

¹1/160 is the median antimitochondrial antibodies titer. ANEA: Anti-nuclear envelope antibody.