Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India

Table 2 Distribution of Cytochrome P450 2E1 genotype in hepatitis cases compared to controls

	Number of individuals (% of group)			Less common allele frequency	χ2value (P value)	OR (95% CI)
	Homozygous-more common allele	Heterozygous	Homozygous-less common allele
RsaI polymorphism	c1/c1	c1/c2	c2/c2
Controls (n = 124)	122 (98.39)	2 (1.61)	0	1.61	ref.
Hepatitis (n = 104)	94 (90.39)	10 (9.71)	0	9.61	0.007	6.489 (1.389-30.326)
DraI polymorphism	DD	DC	CC
Controls (n = 124)	122 (98.39)	2 (1.61)	0	1.61	ref.
Hepatitis (n = 104)	96 (92.31)	4 (3.84)	4 (3.84)	7.69	0.026	5.083 (1.055-24.492)

ata represented as number of subjects showing respective genotype (%); P < 0.05 was considered to be statistically significant, control group was considered as reference group.