Recent standardization of treatment strategy for pancreatic neuroendocrine tumors

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Sep 28, 2010 (publication date) through Apr 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2010; 16(36): 4519-4525
Published online Sep 28, 2010. doi: 10.3748/wjg.v16.i36.4519

Table 1 World Health Organization classification of pancreatic neuroendocrine tumors

WHO classification	Well-differentiated neuroendocrine tumor	Well-differentiated neuroendocrine carcinoma	Poorly-differentiated neuroendocrine carcinoma
Biological behavior	Benign/uncertain behavior	Low malignancy	High malignancy
Metastases	-	+	+
Ki-67/MIB-1 index (%)	< 2	2-20	> 20
Pathological differentiation	Well-differentiated	Well-differentiated	Poorly-differentiated
Vascular invasion	-/+	+	+
Size (diameter)	≤ 2 cm	> 2 cm	Any size

Alteration of the original Table by Klöppel[4]. WHO: World Health Organization.

Citation: Imamura M. Recent standardization of treatment strategy for pancreatic neuroendocrine tumors. World J Gastroenterol 2010; 16(36): 4519-4525
URL: https://www.wjgnet.com/1007-9327/full/v16/i36/4519.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i36.4519