Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy

Figure 3 Effect of matrine on cell cycle distribution in HepG2 cells. A: Matrine treatment significantly increased the proportion of HepG2 cells in G0/G1 phase while decreased the number of HepG2 cells in the S phase. Results were expressed as mean ± SD (n = 3); B-D: Histograms of HepG2 cells incubated with matrine at the concentrations of 0, 0.5 and 1.0 mg/mL. ^bP < 0.01, ^dP <0.001 vs control group.