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©2010 Baishideng.
World J Gastroenterol. Aug 7, 2010; 16(29): 3697-3703
Published online Aug 7, 2010. doi: 10.3748/wjg.v16.i29.3697
Published online Aug 7, 2010. doi: 10.3748/wjg.v16.i29.3697
Table 3 Immunohistochemical study of the global group1n (%)
| Normal expression | Lack of expression | |
| Mismatch repair system proteins | ||
| Mlh1 | 24 (86) | 4 (14) |
| Msh2 | 24 (86) | 4 (14) |
| Msh6 | 23 (88) | 3 (12) |
| Apoptosis | ||
| Bcl-2 | 7 (25) | 21 (75) |
| Cell adhesion | ||
| β-catenin | ||
| Membrane | 24 (86) | 4 (14) |
| Nucleus | 10 (36) | 18 (64) |
| E-cadherin | 19 (73) | 7 (27) |
| Cell cycle markers | ||
| Chk2 | 13 (54) | 11 (46) |
| Cyclin A | 13 (46) | 15 (54) |
| Cyclin D1 | 12 (43) | 16 (57) |
| Cyclin D3 | 12 (43) | 16 (57) |
| Cyclin E | 8 (30) | 19 (70) |
| p16 | 13 (48) | 14 (52) |
| p21 | 14 (56) | 11 (44) |
| p27 | 12 (52) | 11 (48) |
| RB-P | 13 (48) | 14 (52) |
| Skp2 | 12 (46) | 14 (54) |
| Cdk2 | 13 (48) | 14 (52) |
| Proliferation | ||
| p53 | 15 (54) | 13 (46) |
| Ki-67 | 17 (63) | 6 (37) |
| Others | ||
| CK20 | 10 (59) | 7 (41) |
| RAD50 | 10 (63) | 6 (37) |
| SMAD4 | 13 (54) | 11 (46) |
- Citation: Perea J, Alvaro E, Rodríguez Y, Gravalos C, Sánchez-Tomé E, Rivera B, Colina F, Carbonell P, González-Sarmiento R, Hidalgo M, Urioste M. Approach to early-onset colorectal cancer: Clinicopathological, familial, molecular and immunohistochemical characteristics. World J Gastroenterol 2010; 16(29): 3697-3703
- URL: https://www.wjgnet.com/1007-9327/full/v16/i29/3697.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i29.3697