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©2010 Baishideng.
World J Gastroenterol. Jul 28, 2010; 16(28): 3553-3560
Published online Jul 28, 2010. doi: 10.3748/wjg.v16.i28.3553
Published online Jul 28, 2010. doi: 10.3748/wjg.v16.i28.3553
Table 2 Promoter methylation profiles for hMLH1, CDKN2A/p16, and MGMT in the four patient groups n (%)
| Patient group | hMLH1 (tissue) | CDKN2A/p16 (tissue) | MGMT (tissue) | MGMT (blood) | ||||
| M | U | M | U | M | U | M | U | |
| G I (n = 20) | 6/20 (30) | 14/20 (70) | 3/20 (15) | 17/20 (85) | 9/20 (46) | 11/20 (54) | 8/20 (40) | 12/20 (60) |
| G II (n = 18) | 7/18 (39) | 11/18 (61) | 4/18 (22) | 14/18 (78) | 7/18 (39) | 11/18 (61) | 1/18 (6) | 17/18 (94) |
| P = 0.563 | P = 0.581 | P = 0.666 | P = 0.0191 | |||||
| G III (n = 21) | 10/21 (48) | 11/21 (52) | 14/21 (67) | 7/21 (33) | 16/21 (76) | 5/21 (24) | 7/17 (41) | 10/17 (59) |
| P = 0.576 | P = 0.0081 | P = 0.0251 | P = 0.0191 | |||||
| G IV (n = 20) | 13/20 (65) | 7/20 (35) | 14/20 (70) | 6/20 (30) | 18/20 (90) | 2/20 (10) | 11/18 (64) | 7/18 (36) |
| P = 0.279 | P = 0.837 | P = 0.242 | P = 0.245 | |||||
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Citation: Psofaki V, Kalogera C, Tzambouras N, Stephanou D, Tsianos E, Seferiadis K, Kolios G. Promoter methylation status of
hMLH1 ,MGMT , andCDKN2A /p16 in colorectal adenomas. World J Gastroenterol 2010; 16(28): 3553-3560 - URL: https://www.wjgnet.com/1007-9327/full/v16/i28/3553.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i28.3553