Copyright
©2010 Baishideng.
World J Gastroenterol. Jul 21, 2010; 16(27): 3377-3384
Published online Jul 21, 2010. doi: 10.3748/wjg.v16.i27.3377
Published online Jul 21, 2010. doi: 10.3748/wjg.v16.i27.3377
Figure 4 Effects of galangin-treated hepatocellular carcinoma cells on protein expression involved in the mitochondria pathway.
A: The changes of Bax in the mitochondria; B: The changes of cytochrome c and apoptosis-inducing factor (AIF) in the cytosol; C: Caspase-3 and caspase-9 activation, and Poly(ADP-ribose) polymerase (PARP) cleavage induced by galangin. 1: Blank control group; 2: Dimethyl sulfoxide-treatment groups; 3: Cells were treated with 46.25 μmol/L galangin for 24 h; 4: Cells were treated with 92.5 μmol/L galangin for 24 h; 5: Cells were treated with 185 μmol/L galangin for 24 h; 6: Cells were treated with 370 μmol/L galangin for 24 h.
-
Citation: Zhang HT, Luo H, Wu J, Lan LB, Fan DH, Zhu KD, Chen XY, Wen M, Liu HM. Galangin induces apoptosis of hepatocellular carcinoma cells
via the mitochondrial pathway. World J Gastroenterol 2010; 16(27): 3377-3384 - URL: https://www.wjgnet.com/1007-9327/full/v16/i27/3377.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i27.3377