Precise prediction model and simplified scoring system for sustained combined response to interferon-α

Table 4 Significance of baseline factors for sustained combined response to interferon-α therapy

Variable	CR	PR	NR	Mean decrease accuracy	Mean decrease Gini
ALT	2.242	0.860	2.611	1.363	42.806
Duration	0.536	0.599	0.251	0.507	36.340
HBV DNA	0.603	0.742	0.015	0.553	35.713
AST	1.045	-0.243	0.955	0.502	35.488
Genotype	1.101	1.083	3.095	1.269	30.462
Staging	0.737	-0.058	-0.147	0.205	29.400
Grading	-0.033	0.330	-0.035	-0.182	23.283
Age	-0.069	0.094	0.160	0.050	20.944
Gender	-0.125	0.478	-0.084	0.186	14.396

CR: Combined response; PR: Partial response; NR: No response; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HBV: Hepatitis B virus.