Safety of same-day endoscopic ultrasound and endoscopic retrograde cholangiopancreatography under conscious sedation

Table 2 Sedation medication used and dosages n (%)

	Tandem (group A) (n = 54)	EUS only (group B) (n = 56)	P-value1	ERCP only (group C) (n = 53)	P-value2
Sedation type
Conscious sedation	52 (96)	56 (100)	0.24	52 (98)	0.22
GA/propofol	2 (4)	0	0.24	1 (2)	0.22
Medications used for sedation
Meperidine	49 (91)	56 (100)	0.03	44 (83)	0.27
Midazolam	54 (96)	56 (100)	0.24	53 (98)	1.00
Diphenhydramine	16 (30)	4 (7)	0.003	28 (53)	0.02
Promethazine	5 (9)	4 (7)	0.74	0	0.06
Fentanyl	7 (13)	0	0.01	8 (15)	0.12
Total dosage of sedatives used (mean ± SD) (range)
Meperidine (mg)	151.1 ± 64 (25-325)	104 ± 43.6 (25-250)	< 0.0001	104.5 ± 32.5 (25-175)	< 0.0001
Midazolam (mg)	8.5 ± 3.2 (0-16)	6.3 ± 2.4 (2-13)	0.0001	6.9 ± 3.4 (0-16)	0.01
Diphenhydramine (mg)	50 ± 15.8 (25-100)	50 ± 0 (50)	1.00	51.8 ± 9.45 (50-100)	0.64
Promethazine (mg)	25 ± 0 (25)	25 ± 0 (25)	1.00	0	NA
Fentanyl (mcg)	100.0 ± 55.9 (25-175)	0	NA	146.9 ± 54.2 (75-200)	0.12

¹P-value of group A vs group B;

²P-value of group A vs group C. GA: General anesthesia.