Helicobacter pylori in dental plaque and stomach of patients from Northern Brazil

Table 1 Frequency of vacA and cagA genotypes in patients positive for H. pylori DNA in dental plaque and stomach

H. pylori genotypes					Histopathological parametersa						Endoscopic diagnosisb		Total
Stomach		Dental plaque			DI		NA		IM	H. pylori	PU	G (+H)
vacA	cagA	C	D	N	1	2/3	1	2/3	+	+
s1m1	+	42	4	5	21	30	26	25	8	22	7	34/(10)	51
s1m1, s2m2	+	12	-	-	5	7	6	6	3	5	-	10/(2)	12
s2m2	+	-	-	4	2	2	2	2	1	1	1	2/(1)	4
s2m2	-	9	4	15	25	3	22	6	-	11	1	22/(5)	28
Total		63	8	24	53	42	56	39	12	39	9	72/(14)	95

DI: Degree of inflammation; NA: Neutrophilic activity (histopathological scores: 1, light; 2, moderate; 3, intense); IM: Intestinal metaplasia; H. pylori: Helicobacter pylori; G: Gastritis; H: Hiatus hernia; PU: Peptic ulcer; N: Polymerase chain reaction (PCR) negative for H. pylori in dental plaque; C: Identical genotypes in the stomach and dental plaque; D: Distinct genotypes in the stomach and dental plaque.

^aG tests (Yates) = 16.83, P < 0.001 (DI: s1m1 cagA + x s2m2 cagA-); G tests (Yates) = 4.86, P = 0.027 (NA: s1m1 cagA + x s2m2 cagA-);

^bG tests (Yates) = 4.36, P = 0.037 (disease: s1m1 cagA + x s2m2 cagA-).