CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: A meta-analysis

Table 2 Results of meta-analysis for CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk

Analysis	Number of cases/controls	c1c2 + c2c2 vs c1c1		c2c2 vs c1c1
		OR (95% CI)	P/Ph	OR (95% CI)	P/Ph
Overall	4979/6012	1.02 (0.88, 1.19)	0.780/0.094	1.24 (0.93, 1.66)	0.148/0.148
Subgroup analysis for ethnicity
Asian	1126/1560	1.03 (0.88, 1.21)	0.707/0.274	1.35 (0.66, 2.75)	0.414/0.072
Caucasian	3332/3813	1.05 (0.78, 1.41)	0.747/0.066	2.67 (1.03, 6.89)	0.043/0.389
Mixed	521/639	0.84 (0.65, 1.09)	0.196/NA	0.94 (0.52, 1.71)	0.850/NA
Subgroup analysis for tumor location
Colon cancer	907/2188	1.09 (0.83, 1.43)	0.522/0.082	1.22 (0.85, 1.77)	0.279/0.809
Rectum cancer	739/2188	0.89 (0.75, 1.06)	0.206/0.241	0.97 (0.38, 2.43)	0.941/0.014

P_h: P values for heterogeneity from Q test.