Expression and significance of TLR4 and HIF-1α in pancreatic ductal adenocarcinoma

Table 4 Impact of TLR4 and HIF-1α on survival time

Protein	Expression	Estimated survival	95% CI		P
			Lower bound	Upper bound
TLR4	Positive	12.4	10.8	14.0	0.011
	Negative	19.7	15.4	23.9
HIF-1α	Positive	12.8	11.1	14.4	0.005
	Negative	20.2	15.2	25.1
TLR4 positive	HIF-1α positive	11.8	10.1	13.4	0.132
	HIF-1α negative	15.0	10.9	19.2
TLR4 negative	HIF-1α positive	16.5	12.5	20.6	0.089
	HIF-1α negative	21.6	15.1	28.2	0.0141

¹P value compared between patients with both negative TLR4 and HIF-1α expression and those with both positive TLR4 and HIF-1α expression.