©2010 Baishideng.
World J Gastroenterol. May 21, 2010; 16(19): 2421-2427
Published online May 21, 2010. doi: 10.3748/wjg.v16.i19.2421
Published online May 21, 2010. doi: 10.3748/wjg.v16.i19.2421
Table 1 Relationship between EZH2 or STAT6 and clinicopathological features
| Cases | EZH2 expression | P | STAT6 expression | P | |||
| EZH2+ | EZH2- | STAT6+ | STAT6- | ||||
| Tissue | |||||||
| Non-neoplastic samples | 22 | 97 | 0.000 | 50 | 69 | 0.004 | |
| Tumor samples | 83 | 36 | 72 | 47 | |||
| Gender | |||||||
| Female | 47 | 30 | 17 | 0.334 | 24 | 23 | 0.089 |
| Male | 72 | 52 | 20 | 48 | 24 | ||
| Location | |||||||
| Colon | 90 | 62 | 28 | 0.719 | 57 | 33 | 0.268 |
| Rectum | 29 | 21 | 8 | 15 | 14 | ||
| Differentiation | |||||||
| Poor | 21 | 16 | 5 | 0.479 | 16 | 5 | 0.101 |
| Moderate or well | 98 | 67 | 31 | 56 | 42 | ||
| TNM classification | |||||||
| I | 11 | 4 | 7 | 0.049 | 3 | 8 | 0.004 |
| II | 42 | 29 | 13 | 20 | 22 | ||
| III | 44 | 35 | 9 | 32 | 12 | ||
| IV | 22 | 15 | 7 | 17 | 5 | ||
| Depth of wall invasion | |||||||
| T1 | 1 | 1 | 0 | 0.014 | 1 | 0 | 0.188 |
| T2 | 19 | 9 | 10 | 8 | 11 | ||
| T3 | 93 | 71 | 22 | 58 | 35 | ||
| T4 | 6 | 2 | 4 | 5 | 1 | ||
| Lymph node metastasis | |||||||
| No | 55 | 34 | 21 | 0.081 | 25 | 30 | 0.001 |
| Yes | 64 | 49 | 15 | 47 | 16 | ||
| Distant metastasis | |||||||
| M0 | 97 | 66 | 31 | 0.668 | 54 | 43 | 0.024 |
| M1 | 22 | 16 | 6 | 18 | 4 | ||
| Recurrence | |||||||
| No | 86 | 61 | 25 | 0.088 | 53 | 33 | 0.775 |
| Yes | 11 | 6 | 5 | 4 | 7 | ||
- Citation: Wang CG, Ye YJ, Yuan J, Liu FF, Zhang H, Wang S. EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. World J Gastroenterol 2010; 16(19): 2421-2427
- URL: https://www.wjgnet.com/1007-9327/full/v16/i19/2421.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i19.2421