Acute lung injury and ARDS in acute pancreatitis: Mechanisms and potential intervention

Figure 2 Course of acute pancreatitis. A potential development in severe acute pancreatitis with the first “insult” resulting in a pronounce systemic inflammatory response and potential development of organ dysfunction, and in the worst scenario early mortality. Later during the course, combination of organ dysfunction and infection, potentially pronounced after the second “insult” (translocation from the gut, burst of proinflammatory cytokines, surgery, etc.) may result in late mortality. MODS: Multiple organ dysfunction syndrome.