Original Article
Copyright ©2010 Baishideng.
World J Gastroenterol. Apr 28, 2010; 16(16): 1979-1985
Published online Apr 28, 2010. doi: 10.3748/wjg.v16.i16.1979
Figure 3
Figure 3 Assessment of HBV replication ability of drug-resistant HBV mutants using the HBV replication mouse model. The levels of HBV DNA replication intermediates in wild type group were set to 1, and the relative levels of mutant groups were calculated accordingly. A, B: The HBV DNA replication intermediates and relative intensity between wild type injected with pHBV4.1 and telbivudine resistance mutant injected with pLdT (rtM204I); C, D: The HBV DNA replication intermediates and relative intensity between wild type injected with pHBV4.1 and adefovir resistance mutant injected with pADV2 (rtA181V + N236T).