Application of hepatitis B virus replication mouse model

doi:10.3748/wjg.v16.i16.1979

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Apr 28, 2010 (publication date) through Sep 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2010; 16(16): 1979-1985
Published online Apr 28, 2010. doi: 10.3748/wjg.v16.i16.1979

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Figure 3 Assessment of HBV replication ability of drug-resistant HBV mutants using the HBV replication mouse model. The levels of HBV DNA replication intermediates in wild type group were set to 1, and the relative levels of mutant groups were calculated accordingly. A, B: The HBV DNA replication intermediates and relative intensity between wild type injected with pHBV4.1 and telbivudine resistance mutant injected with pLdT (rtM204I); C, D: The HBV DNA replication intermediates and relative intensity between wild type injected with pHBV4.1 and adefovir resistance mutant injected with pADV2 (rtA181V + N236T).

Citation: Gao Z, Liu FJ, Liu L, Zhou TY, Lei J, Xu L, Liu C, Dai J, Chen EQ, Tang H. Application of hepatitis B virus replication mouse model. World J Gastroenterol 2010; 16(16): 1979-1985
URL: https://www.wjgnet.com/1007-9327/full/v16/i16/1979.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i16.1979