Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia

doi:10.3748/wjg.v16.i14.1788

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2010; 16(14): 1788-1794
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1788

Table 4 Risk of SCAG in patients with IL-8-251 and MIF-173 genotypes and H. pylori infection

H. pylori infection	IL-8-251 genotype				MIF-173 genotype
H. pylori infection	TT	OR (95% CI)¹	TA + AA	OR (95% CI)¹	GG	OR (95% CI)¹	C carriers	OR (95% CI)¹
Negative	5/22	1.00	25/37	2.34 (0.95-2.83)	17/40	1.00	13/19	1.60 (0.64-3.97)
Positive	34/34	3.28 (1.09-9.78)	70/44	6.70 (1.29-9.78)	54/60	2.11 (1.07-4.13)	50/18	6.54 (2.97-14.20)

¹OR and 95% CI were calculated by logistic regression, with no progression group as a reference group and adjusted for age, sex. SCAG: Severe chronic atrophic gastritis.

Citation: Li ZW, Wu Y, Sun Y, Liu LY, Tian MM, Feng GS, You WC, Li JY. Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia. World J Gastroenterol 2010; 16(14): 1788-1794
URL: https://www.wjgnet.com/1007-9327/full/v16/i14/1788.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i14.1788