Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia

Table 3 Relation between cytokine gene polymorphisms and development of precursory lesions of GC n (%)

Genotype	Group I (n = 134) OR (95% CI)	Group II (n = 101) OR (95% CI)
IL-8-251
TT	1.00	1.00
TA	1.64 (0.96-2.79)	2.27 (1.25-4.14)
AA	2.62 (1.23-5.72)	1.20 (0.76-1.90)
TA + AA	1.81 (1.06-3.09)	2.07 (1.16-3.69)
MIF-173
GG	1.00	1.00
GC	2.36 (1.38-4.02)	1.50 (0.57-3.94)
CC	1.92 (0.95-3.87)	2.27 (1.16-4.46)
GC + CC	2.07 (1.21-3.55)	3.84 (1.58-9.34)

OR and 95% CI were calculated by logistic regression, with no progression group as a reference group and adjusted for age, sex. OR: Odds ratio.