Influence of efflux pump inhibitors on the multidrug resistance of Helicobacter pylori

Table 1 Induced multidrug resistant MIC profiles of H. pylori (μg/mL)

Strains	Exptl condition	ERY	CIP	TET	CTX	CRO	PIP	CLI	PEN	CAM
4151	Before induction	0.25	0.25	0.5	0.25	0.25	0.25	0.5	0.125	0.5
	After induction	2	0.5	4	1	2	0.5	1	0.25	32
8022	Before induction	0.125	1	1	0.5	0.5	0.5	0.5	0.063	0.25
	After induction	2	1	4	4	4	0.5	0.5	0.25	16
11021	Before induction	0.5	1	1	0.5	0.125	0.25	0.25	0.063	0.5
	After induction	2	2	2	4	4	1	1	0.5	32
11637	Before induction	0.063	0.5	0.25	0.25	0.125	0.25	1	0.25	0.5
	After induction	2	1	4	2	2	0.25	2	1	16
Geometric mean	Before induction	0.177	0.595	0.595	0.354	0.210	0.297	0.500	0.105	0.420
	After induction	2.000	1.000	3.364	2.378	2.828	0.500	1.000	0.420	22.627

ERY: Erythromycin; CIP: Ciprofloxacin; TET: Tetracycline; CTX: Cefotaxime; CRO: Ceftriaxone; PIP: Piperacillin; CLI: Clindamycin; PEN: Penicillin G; CAM: Chloramphenicol; Exptl: Experimental; MIC: Minimum inhibitory concentration.