Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases

Table 2 Presence of metabolic risk factors and liver histology (stage) in NASH cases

	NASH patients (n = 70)1
	Fibrosis				Cirrhosis (%)
	Absent (%)	Perisinusoidal/Pericellular (%)	Periportal (%)	Bridging (%)
Gender
Male	51.4	23.0	14.3	8.60	2.70
Female	38.2	47.0	5.9	8.90	-
Hepatomegaly
(+)2	44.1	31.2	6.3	12.5	5.90
(-)2	44.3	36.5	13.5	7.70	-
Body mass index
18.5-24.9	33.3	0	33.3	33.3	-
25-29.9	38.2	44.1	11.7	5.8	-
30-39.9	46.4	25.0	14.2	10.7	3.12
> 40	25.0	75.0	0	0	-
Central obesity
(+)	46.9	30.6	16.3	6.1	2.04
(-)	65.0	20.0	10.0	5	-
Hypertension
(+)	47.8	42.8	4.7	4.7	-
(-)	58.4	24.4	12.7	4.5	2.04
Diabetes
(+)	28.5	38.0	14.2	14.2	4.76
(-)	53.1	25.5	12.7	8.5	-
Hypertrigly-ceridemia
(+)	50.0	25.0	15.6	9.3	-
(-)	59.3	31.2	6.2	3.1	4.34
Insulin resistance
(+)	53.3	36.6	13.3	3.3	3.33
(-)	65.7	18.4	10.5	2.6	-

¹69 patients with NASH and 1 cirrhotic patient; ²(+): Present; (-): Absent. Presence of diabetes and insulin resistance seemed to increase the severity of fibrosis, but these findings were not significant.