Clinicopathological and prognostic analysis of 429 patients with intrahepatic cholangiocarcinoma

Table 4 Association of CA19-9 with clinicopathological parameters of the patients

	CA19-9 expression
	> 37 U/mL	≤37 U/mL	P value
Gender			0.032
Male	159	135
Female	83	44
Age (yr)			0.040
< 53	112	101
≥ 53	130	78
Surgical procedures			0.106
R0	174	139
R1	44	32
Exploratory laparotomy	24	8
Lymph node metastasis			0.082
Yes	182	148
No	57	30
Macroscopic satellite lesions			0.229
No	184	140
≤ 3	20	20
> 3	38	19
Extrahepatic metastases			0.185
Yes	227	179
No	15	6
Macroscopic tumor thrombi			0.440
Yes	218	157
No	24	22
Microscopic tumor thrombi			0.192
Yes	142	120
No	83	53
Tumor differentiation			0.221
Well	4	1
Moderate	85	52
Poorly	126	105
Number of lesions			0.843
Single	160	120
Multiple	82	59
Tumor size (cm)			0.002
≤ 5	69	72
> 5, ≤ 10	120	64
> 10	37	39
Diffuse type	16	4
HBsAg			0.049
Yes	101	92
No	141	87
Cirrhosis			0.000
Yes	68	80
No	174	99